Multisizer 4 Coulter Counter from Beckman Coulter Life Sciences


The Multisizer 4, the latest COULTER COUNTER designed with the SMART and DPP technologies, offers highly accurate and reliable particle counting and sizing

The Coulter Principle Goes Digital

While retaining and enhancing the analog circuits developed and refined by Coulter over many years - and the Digital Pulse Processor (DPP) used for the first time in the Multisizer 3 - the new Multisizer 4 incorporates the latest advances in both analog and digital circuits. High-speed digitalization of the signal enables the use of multiple parameters for more accurate particle characterization. Plus the possibility of dynamic size measurement is a reality on the Multisizer 4. The measurement data for each particle is analyzed and stored. The data can be analyzed and formatted in numerous ways, or stored and re-analyzed at a later date - no need to analyze the sample again.

Proven Technology

  • More than half a century of experience counting and sizing particles and cells
  • More than 6,000 documented references using the Coulter Principle and nine approved ASTM methods
  • Technology defined by the International Standard ISO 13319 Accurate sizing, counting and high resolution technology preferred by the industry for particle counting and size distribution
  • It provides size, based on direct measurement of a real parameter of a particle - its volume. Color or refractive index does not affect results
  • Capable of counting and sizing particles at concentration levels not detected by other technologies
  • Dynamic size measurement. Pulse time stamp allows size change measurement in real time

Superior Instrument Design

  • Ease-of-use. Instrument operation is completely controlled from the computer. Intuitive software with wizards are ideal for beginners, while simple menus assist experienced operators
  • Volumetric metering pump is compatible with both aqueous and organic fluids
  • Extended dynamic range
  • Environmentally friendly, mercury-free metering system
  • Improved performance in dusty environments
  • Sample management system using Smart Technology provides a great level of consistency for running the analyses
  • EZAccess fluid management system
  • Electronic aperture blockage detection
  • Automatic startup user-selectable routine

Quality Assurance Friendly System

  • User-defined Standard Operation Procedure
  • Multiple security levels
  • Software enables 21 CFR Part 11 compliance
  • Powerful and flexible software allows the processing and presentation of data to fit all needs, including industrial applications, biological applications, academic applications, research and quality control
  • Automated calibration and calibration verification ensures reliable results for both size and counts
  • V-Check validation package offers a comprehensive solution for today’s quality assurance requirements
  • Certification program to ensure instrument performance


  • Increased dynamic range
  • Increased resolution
  • Proven technology
  • Superior instrument design
  • Quality assurance friendly
  • Digital Pulse Processor (DPP)
  • Dynamic size measurements
  • Provides number, volume, mass and surface area size distributions in one measurement
  • V-Check (IQ, OQ, PQ) instrument validation
Product Link

Click here to see to more of what Beckman Coulter can do for you!

Beckman Coulter Life Sciences Contact Information

Beckman Coulter Life Sciences

250 S. Kraemer Blvd
Brea, CA 92821-6232

(800) 742-2345

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